Selective Bibliography of Dr. Yinling Hu
Cancer Innovation Laboratory, NCI

"Opportunistic Candida albicans and Cladosporium Target EGFR Family Members, Tweak Innate Immune Responses, and Promote Carcinogenesis"

Wednesday, October 25, 2023

1.  Xiao Z, Shi G, Xi S, Singh AK, Willette-Brown J, Li X, Zhu F, Su L, Wu X, Schrump DS, Hu Y
A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop
Cell Death and Disease 13 (10):885 Oct 21 2022

2.  Song NY, Li X, Ma B, Willette-Brown J, Zhu F, Jiang C, Su L, Shetty J, Zhao Y, Shi G, Banerjee S, Wu X, Tran B, Nussinov R, Karin M, Hu Y
IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines
Proceedings of the National Academy of Sciences of the United States of America 119 (6):e2120956119 Feb 8 2022

3.  Zhu F, Willette-Brown J, Zhang J, Ferre EMN, Sun Z, Wu X, Lionakis MS, Hu Y
NLRP3 Inhibition Ameliorates Severe Cutaneous Autoimmune Manifestations in a Mouse Model of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Like Disease
Journal of Investigative Dermatology 141 (6):1404-1415 Jun 2021

4.  Su H, Yang F, Fu R, Li X, French R, Mose E, Pu X, Trinh B, Kumar A, Liu J, Antonucci L, Todoric J, Liu Y, Hu Y, Diaz-Meco MT, Moscat J, Metallo CM, Lowy AM, Sun B, Karin M
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
Cancer Cell 39 (5):678-693.e11 May 10 2021

5.  Gray Z, Shi G, Wang X, Hu Y
Macrophage inducible nitric oxide synthase promotes the initiation of lung squamous cell carcinoma by maintaining circulated inflammation
Cell Death and Disease 9 (6):642 May 29 2018

6.  Song NY, Zhu F, Wang Z, Willette-Brown J, Xi S, Sun Z, Su L, Wu X, Ma B, Nussinov R, Xia X, Schrump DS, Johnson PF, Karin M, Hu Y
IKKalpha inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways
Proceedings of the National Academy of Sciences of the United States of America 115 (4):E812-E821 Jan 23 2018

7.  Zhu F, Willette-Brown J, Song NY, Lomada D, Song Y, Xue L, Gray Z, Zhao Z, Davis SR, Sun Z, Zhang P, Wu X, Zhan Q, Richie ER, Hu Y
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis
Cell Host and Microbe 21 (4):478-493 e7 Apr 12 2017

8.  Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M, Nunez G, Dubyak G, Hu Y, Li X
IKKalpha negatively regulates ASC-dependent inflammasome activation
Nature Communications 5 4977 Sep 30 2014

9.  Xia X, Liu S, Xiao Z, Zhu F, Song NY, Zhou M, Liu B, Shen J, Nagashima K, Veenstra TD, Burkett S, Datla M, Willette-Brown J, Shen H, Hu Y
An IKKalpha-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity
Cell Reports 5 (5):1243-55 Dec 12 2013

10. Xiao Z, Jiang Q, Willette-Brown J, Xi S, Zhu F, Burkett S, Back T, Song NY, Datla M, Sun Z, Goldszmid R, Lin F, Cohoon T, Pike K, Wu X, Schrump DS, Wong KK, Young HA, Trinchieri G, Wiltrout RH, Hu Y 
The pivotal role of IKKalpha in the development of spontaneous lung squamous cell carcinomas
Cancer Cell 23 (4):527-40 Apr 15 2013

11.  Balkhi MY, Willette-Brown J, Zhu F, Chen Z, Liu S, Guttridge DC, Karin M, Hu Y
IKKalpha-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis
Blood 119 (23):5467-77 Jun 7 2012

12.  Liu B, Willette-Brown J, Liu S, Chen X, Fischer SM, Hu Y
IKKalpha represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin
Cell Death and Differentiation 18 (12):1854-64 Dec 2011

13.  Liu B, Xia X, Zhu F, Park E, Carbajal S, Kiguchi K, DiGiovanni J, Fischer SM, Hu Y
IKKalpha is required to maintain skin homeostasis and prevent skin cancer
Cancer Cell 14 (3):212-25 Sep 9 2008