Selective Bibliography of Dr. Ludmila Szabova
Laboratory Animal Sciences Program, NCI

“Mouse Models for Ovarian and Breast Cancer and Their Use in Preclinical Research”
Wednesday, March 19, 2025 

1. Lee U, Szabova L, Collins VJ, Gordon M, Johnson K, Householder D, Jorgensen S, Lu L, Bassel L, Elloumi F, Peer CJ, Nelson AE, Varriano S, Varma S, Roberts RD, Ohler ZW, Figg WD, Sharan SK, Pommier Y, Heske CM
   Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response
   Frontiers in Cell and Developmental Biology 12 1462840 Oct 23 2024
2. Szabova L, Gordon MB, Lu L, Pate N, Bassel L, Iacovelli AJ, Karim B, Homan PJ, Householder DB, Guerin TM, Burkett S, Day AM, Custer W, Weaver Ohler Z
   Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins
   Breast Cancer Research 24 (1):75 Nov 4 2022

3. Gopinathan G, Berlato C, Lakhani A, Szabova L, Pegrum C, Pedrosa AR, Laforets F, Maniati E, Balkwill FR
   Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer
   Molecular Cancer Therapeutics 21 (6):1030-1043 Jun 1 2022

4. Blondal T, Gamba C, Møller Jagd L, Su L, Demirov D, Guo S, Johnston CM, Riising EM, Wu X, Mikkelsen MJ, Szabova L, Mouritzen P
   Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing
   Methods 191 68-77 Jul 2021

5. Maniati E, Berlato C, Gopinathan G, Heath O, Kotantaki P, Lakhani A, McDermott J, Pegrum C, Delaine-Smith RM, Pearce OMT, Hirani P, Joy JD, Szabova L, Perets R, Sansom OJ, Drapkin R, Bailey P, Balkwill FR
   Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
   Cell Reports 30 (2):525-540.e7 Jan 14 2020

6. Marzi L, Szabova L, Gordon M, Weaver Ohler Z, Sharan SK, Beshiri ML, Etemadi M, Murai J, Kelly K, Pommier Y
   The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib
   Clinical Cancer Research 25 (20):6206-6216 Oct 15 2019

7. Szabova L, Karim B, Gordon M, Lu L, Pate N, Ohler ZW
   A Transplantable Syngeneic Allograft Mouse Model for Nongestational Choriocarcinoma of the Ovary
   Veterinary Pathology 56 (3):399-403 May 2019

8. Szabova L, Bupp S, Kamal M, Householder DB, Hernandez L, Schlomer JJ, Baran ML, Yi M, Stephens RM, Annunziata CM, Martin PL, Van Dyke TA, Weaver Ohler Z, Difilippantonio S
   Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer
   PLoS One 9 (4):e95649 Apr 8 2014

9. Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, Householder DB, Baran ML, Yi M, Song Y, Sun W, McDunn JE, Martin PL, Van Dyke T, Difilippantonio S
   Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer
   Cancer Research 72 (16):4141-53 Aug 15 2012

10. Szabova L, Son MY, Shi J, Sramko M, Yamada SS, Swaim WD, Zerfas P, Kahan S, Holmbeck K
    Membrane-type MMPs are indispensable for placental labyrinth formation and development
    Blood 116 (25):5752-61 Dec 16 2010