Selective Bibliography of Dr. Stuart F.J. Le Grice
Basic Research Laboratory, NCI

“Moving Towards RNA-targeted Therapeutics - a Last Word”
Wednesday, November 18, 2020

1.  Bak E, Miller JT, Noronha A, Tavis J, Gallicchio E, Murelli RP, Le Grice SFJ
3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis
Molecules 25 (19):Sep 27 2020

2.  Shilo A, Tosto FA, Rausch JW, Le Grice SFJ, Misteli T
Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome
Nucleic Acids Research 47 (11):5922-5935 Jun 20 2019

3.  Abulwerdi FA, Xu W, Ageeli AA, Yonkunas MJ, Arun G, Nam H, Schneekloth JS, Jr., Dayie TK, Spector D, Baird N, Le Grice SFJ
Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1
ACS Chemical Biology 14 (2):223-235 Feb 15 2019

4.  Dai Y, Wynn JE, Peralta AN, Sherpa C, Jayaraman B, Li H, Verma A, Frankel AD, Le Grice SF, Santos WL
Discovery of a Branched Peptide That Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication
Journal of Medicinal Chemistry 61 (21):9611-9620 Nov 8 2018

5.  Sherpa C, Rausch JW, Le Grice SF
Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2
Nucleic Acids Research 46 (19):10432-10447 Nov 2 2018

6.  LeBlanc RM, Longhini AP, Le Grice SFJ, Johnson BA, Dayie TK
Combining asymmetric 13C-labeling and isotopic filter/edit NOESY: a novel strategy for rapid and logical RNA resonance assignment
Nucleic Acids Research 45 (16):e146 Sep 19 2017

7.  Sztuba-Solinska J, Rausch JW, Smith R, Miller JT, Whitby D, Le Grice SFJ
Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA: a structural scaffold for nuclear, cytoplasmic and viral proteins
Nucleic Acids Research 45 (11):6805-6821 Jun 20 2017

8.  Crawford DW, Blakeley BD, Chen PH, Sherpa C, Le Grice SF, Laird-Offringa IA, McNaughton BR
An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription
ACS Chemical Biology 11 (8):2206-15 Aug 19 2016

9.  Shapiro BA, Le Grice SF
Advances in RNA structure determination
Methods 103 1-3 Jul 1 2016

10.  Le Grice SF
Targeting the HIV RNA genome: high-hanging fruit only needs a longer ladder
Current Topics in Microbiology and Immunology 389 147-69 2015