Selective Bibliography of Dr. Ruth Nussinov
Cancer Innovation Laboratory, NCI

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Wednesday, January 15, 2025

1. Xiang H, Zeng L, Hou L, Li K, Fu Z, Qiu Y, Nussinov R, Hu J, Rosen-Zvi M, Zeng X, Cheng F 
   A molecular video-derived foundation model for scientific drug discovery 
   Nature Communications 15 (1):9696 Nov 8 2024
2. Xu L, Jang H, Nussinov R 
   Capturing Autoinhibited PDK1 Reveals the Linker's Regulatory Role, Informing Innovative Inhibitor Design 
   Journal of Chemical Information and Modeling 64 (19):7709-7724 Oct 14 2024
3. Bergman MT, Zhang W, Liu Y, Jang H, Nussinov R 
   Binding Modalities and Phase-Specific Regulation of Cyclin/Cyclin-Dependent Kinase Complexes in the Cell Cycle  
   The Journal of Physical Chemistry B 128 (39):9315-9326 Oct 3 2024
4. Li T, Ren X, Luo X, Wang Z, Li Z, Luo X, Shen J, Li Y, Yuan D, Nussinov R, Zeng X, Shi J, Cheng F 
   A Foundation Model Identifies Broad-Spectrum Antimicrobial Peptides against Drug-Resistant Bacterial Infection  
   Nature Communications 15 (1):7538 Aug 30 2024
5. Lin Y, Ramelot TA, Senyuz S, Gursoy A, Jang H, Nussinov R, Keskin O, Zheng Y 
   Tumor-derived RHOA mutants interact with effectors in the GDP-bound state  
   Nature Communications 15 (1):7176 Aug 21 2024
6. Zhang W, Liu Y, Jang H, Nussinov R 
   Slower CDK4 and faster CDK2 activation in the cell cycle 
   Structure 32 (8):1269-1280.e2 Aug 8 2024
7. Magits W, Steklov M, Jang H, Sewduth RN, Florentin A, Lechat B, Sheryazdanova A, Zhang M, Simicek M, Prag G, Nussinov R, Sablina A 
   K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins 
   The EMBO Journal 43 (14):2862-2877 Jul 2024
8. Lu W, Cui J, Wang W, Hu Q, Xue Y, Liu X, Gong T, Lu Y, Ma H, Yang X, Feng B, Wang Q, Zhang N, Xu Y, Liu M, Nussinov R, Cheng F, Ji H, Huang J 
   PPIA dictates NRF2 stability to promote lung cancer progression 
   Nature Communications 15 (1):4703 Jun 3 2024
9. Liu Y, Jang H, Nussinov R 
   SHP2-EGFR States in Dephosphorylation Can Inform Selective SHP2 Inhibitors, Dampening RasGAP Action 
   The Journal of Physical Chemistry B 128 (21):5175-5187 May 30 2024
10. Qiu Y, Hou Y, Gohel D, Zhou Y, Xu J, Bykova M, Yang Y, Leverenz JB, Pieper AA, Nussinov R, Caldwell JZK, Brown JM, Cheng F 
    Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease 
    Cell Reports 43 (5):114128 May 28 2024