Selective Bibliography of Dr. Doug Johnson
Biogen

Thursday, October 10, 2019

1.  Fang YZ, Judkins JC, Boyd SJ, Ende CWA, Rohlfing K, Huang Z, Xie YX, Johnson DS, Fox JM
Studies on the stability and stabilization of trans-cyclooctenes through radical inhibition and silver (I) metal complexation
Tetrahedron 75 (32):4307-4317 Aug 2019

2.  Xu H, Jesson MI, Seneviratne UI, Lin TH, Sharif MN, Xue L, Nguyen C, Everley RA, Trujillo JI, Johnson DS, Point GR, Thorarensen A, Kilty I, Telliez JB
PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor
ACS Chemical Biology 14 (6):1235-1242 Jun 21 2019

3.  Huang Z, Ogasawara D, Seneviratne UI, Cognetta AB, 3rd, Am Ende CW, Nason DM, Lapham K, Litchfield J, Johnson DS, Cravatt BF
Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474
ACS Chemical Biology 14 (2):192-197 Feb 15 2019

4.  McAllister LA, Butler CR, Mente S, O'Neil SV, Fonseca KR, Piro JR, Cianfrogna JA, Foley TL, Gilbert AM, Harris AR, Helal CJ, Johnson DS, Montgomery JI, Nason DM, Noell S, Pandit J, Rogers BN, Samad TA, Shaffer CL, da Silva RG, Uccello DP, Webb D, Brodney MA
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation
Journal of Medicinal Chemistry 61 (7):3008-3026 Apr 12 2018

5.  Fang Y, Zhang H, Huang Z, Scinto SL, Yang JC, Am Ende CW, Dmitrenko O, Johnson DS, Fox JM
Photochemical syntheses, transformations, and bioorthogonal chemistry of trans-cycloheptene and sila trans-cycloheptene Ag(i) complexes
Chemical Science 9 (7):1953-1963 Feb 21 2018

6.  Butler CR, Beck EM, Harris A, Huang Z, McAllister LA, Am Ende CW, Fennell K, Foley TL, Fonseca K, Hawrylik SJ, Johnson DS, Knafels JD, Mente S, Noell GS, Pandit J, Phillips TB, Piro JR, Rogers BN, Samad TA, Wang J, Wan S, Brodney MA
Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
Journal of Medicinal Chemistry  60 (23):9860-9873 Dec 14 2017

7.  Johnson DS, Majmudar JD
Bond with Me If You Can! Natural Product, Covalent Ligand, and Reactivity-Based Probe Compete for Cysteine in PP2A Complex
Cell Chemical Biology 24 (11):1317-1318 Nov 16 2017

8.  Pettersson M, Johnson DS, Rankic DA, Kauffman GW, Am Ende CW, Butler TW, Boscoe B, Evrard E, Helal CJ, Humphrey JM, Stepan AF, Stiff CM, Yang E, Xie L, Bales KR, Hajos-Korcsok E, Jenkinson S, Pettersen B, Pustilnik LR, Ramirez DS, Steyn SJ, Wood KM, Verhoest PR
Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione gamma-secretase modulators with robust central efficacy
MedChemComm 8 (4):730-743 Apr 1 2017

9.  Gertsik N, Am Ende CW, Geoghegan KF, Nguyen C, Mukherjee P, Mente S, Seneviratne U, Johnson DS, Li YM
Mapping the Binding Site of BMS-708163 on gamma-Secretase with Cleavable Photoprobes
Cell Chemical Biology 24 (1):3-8 Jan 19 2017

10.  Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of beta-secretase inhibitors
Nature Communications 7 13042 Oct 11 2016